{"id":13284,"date":"2024-03-19T10:45:09","date_gmt":"2024-03-19T10:45:09","guid":{"rendered":"https:\/\/pruefer.eu\/?p=13284"},"modified":"2024-04-04T09:16:46","modified_gmt":"2024-04-04T09:16:46","slug":"%e4%bb%8e-upc-%e7%9a%84%e8%a7%92%e5%ba%a6%e6%9d%a5%e7%9c%8b%e6%9d%83%e5%88%a9%e8%a6%81%e6%b1%82%e7%9a%84%e8%a7%a3%e9%87%8a%e3%80%81%e9%99%88%e8%bf%b0%e8%b4%a3%e4%bb%bb%e5%92%8c%e4%ba%8b%e5%ae%9e","status":"publish","type":"post","link":"https:\/\/pruefer.eu\/zh-hans\/2024\/03\/19\/%e4%bb%8e-upc-%e7%9a%84%e8%a7%92%e5%ba%a6%e6%9d%a5%e7%9c%8b%e6%9d%83%e5%88%a9%e8%a6%81%e6%b1%82%e7%9a%84%e8%a7%a3%e9%87%8a%e3%80%81%e9%99%88%e8%bf%b0%e8%b4%a3%e4%bb%bb%e5%92%8c%e4%ba%8b%e5%ae%9e\/","title":{"rendered":"\u4ece UPC \u7684\u89d2\u5ea6\u6765\u770b\u6743\u5229\u8981\u6c42\u7684\u89e3\u91ca\u3001\u9648\u8ff0\u8d23\u4efb\u548c\u4e8b\u5b9e\u8bc1\u660e &#8211; UPC_CoA_335\/2023"},"content":{"rendered":"\n\n\n<!-- blogbeitrag-->\n\n<section id=\"blogbeitrag-block_b95661cc4fe0777a320c8e9fd3ce6c51\" class=\"block blogbeitrag page-section bg-white\">\n    <div class=\"container normalpadding\">\n        <div class=\"row justify-content-center\">\n            <div class=\"col-lg-10 text-start\">\n                <div class=\"bilder\">\n                                <div>\n                <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"495\" src=\"https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-700x495.jpg\" class=\"attachment-bild-modul size-bild-modul\" alt=\"\" srcset=\"https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-700x495.jpg 700w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-300x212.jpg 300w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-1024x724.jpg 1024w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-768x543.jpg 768w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-1536x1086.jpg 1536w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-2048x1448.jpg 2048w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-1920x1358.jpg 1920w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-400x283.jpg 400w, https:\/\/pruefer.eu\/wp-content\/uploads\/2024\/03\/UPC_post-NEU-1-150x106.jpg 150w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/div>\n                                <\/div>\n                <p>UPC \u7684\u9996\u6279\u88c1\u51b3\u5df2\u7ecf\u4e0b\u8fbe\uff0c\u4e86\u89e3 UPC \u5728\u5e7f\u6cdb\u8ba8\u8bba\u7684\u6743\u5229\u8981\u6c42\u89e3\u91ca\u3001\u4e8b\u5b9e\u9648\u8ff0\u548c\u4e3e\u8bc1\u8d23\u4efb\u4ee5\u53ca\u521b\u9020\u6027\u8003\u8651\u7b49\u95ee\u9898\u4e0a\u7684\u7acb\u573a\u5c06\u662f\u4ee4\u4eba\u5174\u594b\u7684\u3002<\/p>\n<p><strong>1. \u6743\u5229\u8981\u6c42\u89e3\u91ca\u7684\u4ecb\u7ecd\u4ee5\u53ca\u4e0e\u6b27\u6d32\u4e13\u5229\u5c40\u7684\u6bd4\u8f83<\/strong><br 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&#8220;\u539f\u5219\uff0c\u5728\u89e3\u91ca\u6743\u5229\u8981\u6c42\u7279\u5f81\u65f6\uff0c\u660e\u786e\uff08\u6e05\u6670\uff09\u7684\u6743\u5229\u8981\u6c42\u63aa\u8f9e\u5fc5\u987b\u4f18\u5148\u4e8e\u8bf4\u660e\uff0c<u>\u56e0\u6b64\u53ea\u6709\u5728\u6743\u5229\u8981\u6c42\u7279\u5f81\u4e0d\u660e\u786e\u65f6\uff0c\u624d\u6709\u53ef\u80fd\u53c2\u8003\u8bf4\u660e\u6765\u89e3\u91ca\u6743\u5229\u8981\u6c42\u3002<\/u><\/p>\n<p>\u5728 T 0169\/20 \u53f7\u6848\u4ef6\u4e2d\uff0c\u59d4\u5458\u4f1a\u8ba4\u4e3a\uff0c<u>\u300a\u6b27\u6d32\u4e13\u5229\u516c\u7ea6\u300b\u7b2c 84 \u6761\u7684\u89c4\u5b9a<\/u>\uff0c\u7279\u522b\u662f\u7b2c 84 \u6761\u7b2c 2 \u53e5\uff0c\u4ee5\u53ca\u300a\u6b27\u6d32\u4e13\u5229\u516c\u7ea6\u300b<u>\u7b2c 42 \u548c 43 \u6761\u7684\u89c4\u5b9a<\/u>\uff0c\u4e3a\u5728\u8bc4\u4f30\u4e13\u5229\u6027\u65f6\u7684\u6743\u5229\u8981\u6c42\u89e3\u91ca\u63d0\u4f9b\u4e86\u5145\u5206\u7684\u6cd5\u5f8b\u4f9d\u636e\u3002\u300a\u6b27\u6d32\u4e13\u5229\u516c\u7ea6\u300b\u7b2c 69 \u6761\u4ec5\u7528\u4e8e\u786e\u5b9a\u4fdd\u62a4\u8303\u56f4\uff0c\u4ee5\u5ba1\u67e5\u662f\u5426\u7b26\u5408\u300a\u6b27\u6d32\u4e13\u5229\u516c\u7ea6\u300b\u7b2c 123(3)\u6761\u7684\u89c4\u5b9a\uff0c\u4ee5\u53ca\u5728\u4fb5\u6743\u8bc9\u8bbc\u4e2d\u4f7f\u7528\uff08\u4e0e T 1473\/19 \u76f8\u53cd\uff09\u3002\u59d4\u5458\u4f1a\u8fdb\u4e00\u6b65\u5f97\u51fa\u7ed3\u8bba 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&#8220;\u8bc4\u4f30\u3002\u5982\u679c\u4e13\u5229\u65e0\u6548\u7684<strong>\u53ef\u80fd\u6027\u66f4\u5927<\/strong>\uff0c\u5219\u521d\u6b65\u7981\u4ee4\u5c06\u5931\u6548\u3002\u8fd9\u4e00\u6982\u5ff5\u5f52\u7ed3\u4e3a\u201c\u7b80\u5355\u201d\u95ee\u9898\uff1a\u5229\u88ab\u8ba4\u5b9a\u4e3a\u4e0d\u5177\u6709\u65b0\u9896\u6027\u6216\u4e0d\u5177\u6709\u521b\u9020\u6027\u7684\u53ef\u80fd\u6027\u66f4\u5927\uff1f\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u7edf\u4e00\u4e13\u5229\u6cd5\u9662\u4e0d\u5e94\u5728\u4e13\u5229\u4fb5\u6743\u8bc9\u8bbc\u4e2d\u6388\u4e88\u521d\u6b65\u7981\u4ee4\u3002<br \/>\n\u56e0\u6b64\uff0c\u8be5\u5224\u51b3\u4e3a UPC \u63d0\u4f9b\u4e86\u4e00\u4e2a\u5171\u540c\u7684\u6807\u51c6\uff0c\u6709\u522b\u4e8e\u5404\u56fd\u6cd5\u9662\u4e4b\u95f4\u5404\u79cd\u76f8\u4e92\u51b2\u7a81\u7684\u5224\u51b3\u3002<\/p>\n<p><strong>3. UPC \u524d\u7684\u5bf9\u521b\u9020\u6b65\u9aa4\u7684\u8003\u8651<\/strong><\/p>\n<p>\u5728\u672c\u6848\uff08UPC_CoA_335\/2023\uff09\u4e2d\uff0c\u4e0a\u8bc9\u6cd5\u5ead\u5f97\u51fa\u7684\u7ed3\u8bba\u662f\uff0c\u6743\u5229\u8981\u6c421\u7684\u4e3b\u9898\u88ab\u8bc1\u660e\u662f\u663e\u800c\u6613\u89c1\u7684\u53ef\u80fd\u6027\u66f4\u5927\u3002\u6709\u8da3\u7684\u662f\uff0c\u4e0a\u8bc9\u6cd5\u5ead\u7684\u8fd9\u4e00\u51b3\u5b9a\u63a8\u7ffb\u4e86\u4e00\u5ba1\u6cd5\u9662\u5173\u4e8e\u8fd9\u4e00\u90e8\u5206\u7684\u76f8\u53cd\u88c1\u51b3\u3002<\/p>\n<p>\u4e0a\u8bc9\u6cd5\u5ead\u5f97\u51fa\u8fd9\u4e00\u7ed3\u8bba\u7684\u4f9d\u636e\u662f\uff0c\u76f8\u5173\u73b0\u6709\u6280\u672f\u6587\u732e D6 \u4e0e\u6743\u5229\u8981\u6c42 1 \u4e4b\u95f4\u7684\u552f\u4e00\u533a\u522b\u5728\u4e8e\uff0cD6 \u6ca1\u6709\u516c\u5f00\u6743\u5229\u8981\u6c421\u7684\u65b9\u6cd5\u65e8\u5728\u68c0\u6d4b\u7ec6\u80de\u6216\u7ec4\u7ec7\u6837\u672c\u4e2d\u7684\u591a\u79cd\u5206\u6790\u7269\u8fd9\u4e00\u7279\u5f81\u3002\u76f8\u53cd\uff0cD6 \u516c\u5f00\u4e86\u4e00\u79cd\u65e8\u5728\u68c0\u6d4b &#8220;\u6269\u589e DNA \u5206\u5b50&#8221;\uff08ASMs\uff09\u7684\u65b9\u6cd5\uff0c\u800c\u8fd9\u79cd\u5206\u5b50\u5e76\u4e0d\u5b58\u5728\u4e8e\u7ec6\u80de\u6216\u7ec4\u7ec7\u6837\u672c\u4e2d\uff0c\u719f\u7ec3\u6280\u672f\u4eba\u5458\u4e5f\u4e0d\u4f1a\u5c06\u5176\u89c6\u4e3a\u4e13\u5229\u610f\u4e49\u4e0a\u7684\u7ec6\u80de\u6216\u7ec4\u7ec7\u6837\u672c\u3002\u56e0\u6b64\uff0c\u65b0\u9896\u6027\u5f97\u5230\u4e86\u8ba4\u53ef\u3002<\/p>\n<p>\u5173\u4e8e\u521b\u9020\u6027\uff0c\u4e0a\u8bc9\u6cd5\u5ead\u8fdb\u4e00\u6b65\u6307\u51fa\uff0c\u5bfb\u6c42\u5f00\u53d1\u7528\u4e8e\u68c0\u6d4b\u6837\u54c1\u4e2d\u76ee\u6807\u5206\u5b50\u7684\u9ad8\u901a\u91cf\u5149\u5b66\u591a\u91cd\u5206\u6790\u65b9\u6cd5\u7684\u6280\u672f\u4eba\u5458\u4f1a\u8003\u8651 D6\uff0c\u56e0\u4e3a\u8be5\u6587\u4ef6\u516c\u5f00\u4e86\u4e00\u79cd\u68c0\u6d4b\u591a\u79cd ASMs \u7684\u65b9\u6cd5\u3002\u4ece\u8be5\u6587\u732e\u51fa\u53d1\uff0c\u5e76\u8003\u8651\u5230\u5728\u4f18\u5148\u6743\u65e5\u5185\u5bf9\u591a\u91cd\u5206\u6790\u6280\u672f\u7684\u9700\u6c42\uff0c\u6280\u672f\u4eba\u5458\u4e5f\u4f1a\u8003\u8651\u5c06 D6 \u7684\u65b9\u6cd5\u8f6c\u79fb\u5230\u539f\u4f4d\u73af\u5883\u4e2d\uff0c\u53e6\u4e00\u4efd\u6587\u732e\uff08B30\uff09\u4e5f\u8bc1\u660e\u4e86\u8fd9\u4e00\u70b9\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5728\u8bba\u8bc1\u4e3a\u4ec0\u4e48\u719f\u7ec3\u4eba\u5458\u5728\u9047\u5230\u56f0\u96be\u65f6\u4e0d\u4f1a\u56e0\u4e3a\u6210\u529f\u7684\u53ef\u80fd\u6027\u4e0d\u8db3\u800c\u4e0d\u8fdb\u884c\u8bd5\u9a8c\u65f6\uff0c\u4e0a\u8bc9\u6cd5\u5ead\u63d0\u5230\u4e86\u745e\u5178\u77e5\u8bc6\u4ea7\u6743\u5c40\u7684\u54a8\u8be2\u62a5\u544a\uff08B10\uff0c\u7b2c 5 \u9875\uff09\u3002<\/p>\n<p>\u4e0a\u8bc9\u6cd5\u5ead\u5f97\u51fa\u7ed3\u8bba\u8ba4\u4e3a\uff0c\u7531\u4e8e\u7f3a\u4e4f\u521b\u9020\u6027\uff0c\u4e89\u8bae\u4e13\u5229\u5f88\u6709\u53ef\u80fd\u5728\u6848\u60c5\u5ba1\u7406\u4e2d\u88ab\u8bc1\u660e\u65e0\u6548\uff0c\u5e76\u88c1\u5b9a\u6ca1\u6709\u8db3\u591f\u7684\u4f9d\u636e\u7b7e\u53d1\u521d\u6b65\u7981\u4ee4\u3002<\/p>\n<p>\u53ef\u4f9b\u53c2\u8003\u7684\u4fe1\u606f:<\/p>\n<ul>\n<li>\u6839\u636e\u300a\u6b27\u6d32\u4e13\u5229\u516c\u7ea6\u300b\u7b2c 69 \u6761\u5e76\u7ed3\u5408\u6b64\u6761\u7684\u89e3\u91ca\u8bae\u5b9a\u4e66\uff0c\u4e0a\u8bc9\u6cd5\u5ead\u88c1\u5b9a\uff0c\u63cf\u8ff0\u548c\u9644\u56fe\u5fc5\u987b\u59cb\u7ec8\u4f5c\u4e3a\u89e3\u91ca\u4e13\u5229\u6743\u5229\u8981\u6c42\u7684\u89e3\u91ca\u6027\u8f85\u52a9\u6750\u6599\uff0c\u800c\u4e0d\u4ec5\u4ec5\u662f\u4e3a\u4e86\u89e3\u51b3\u6743\u5229\u8981\u6c42\u4e2d\u7684\u6a21\u7cca\u4e4b\u5904\u3002<\/li>\n<li>&#8220;\u8db3\u591f\u7684\u786e\u5b9a\u6027 &#8220;\u8981\u6c42\u4e0a\u8bc9\u6cd5\u5ead\u5728\u6743\u8861\u5404\u79cd\u53ef\u80fd\u6027\u540e\u8ba4\u4e3a\u67d0\u4e9b\u4e8b\u60c5 &#8220;\u81f3\u5c11\u6bd4\u4e0d\u53ef\u80fd\u53d1\u751f\u7684\u53ef\u80fd\u6027\u5927&#8221;\u3002<\/li>\n<li>\u770b\u6765\uff0c\u4e0a\u8bc9\u6cd5\u9662\u5e76\u4e0d\u50cf\u6b27\u6d32\u4e13\u5229\u5c40\u90a3\u6837\uff0c\u8981\u6c42 &#8220;\u5408\u7406\u9884\u671f\u6210\u529f&#8221;\/\u89e3\u51b3\u6240\u63d0\u51fa\u95ee\u9898\u7684\u52a8\u673a\u8fbe\u5230\u540c\u6837\u7684\u6c34\u5e73\uff0c\u624d\u80fd\u8ba4\u4e3a\u6240\u8981\u6c42\u7684\u4e3b\u9898\u662f\u663e\u800c\u6613\u89c1\u7684\u3002UPC \u662f\u5426\u4f1a\u503e\u5411\u4e8e\u66f4 &#8220;\u5fb7\u56fd\u5f0f &#8220;\u7684\u65b9\u6cd5\uff0c\u5373\u6280\u672f\u4eba\u5458\u901a\u5e38\u4e0d\u9700\u8981\u90a3\u4e48\u591a\u52a8\u673a\u6765\u4fee\u6539\u73b0\u6709\u6280\u672f\uff0c\u8fd8\u6709\u5f85\u89c2\u5bdf[2] \u3002<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[1] GRUR 2022, 811 &#8211; \u83f2\u5c3c\u514b\u65af\u7535\u6c14\/\u54c8\u5ef7<br \/>\n\u6155\u5c3c\u9ed1\u5730\u533a\u6cd5\u9662\uff1a<br \/>\n2022 \u5e74 9 \u6708 29 \u65e5\u7684\u88c1\u51b3\uff0cAz. 7 O 4716\/22\uff1b\u4ee5\u53ca 2022 \u5e74 10 \u6708 27 \u65e5\uff0cAz. 7 O 10295\/22:<br \/>\n\u63a8\u5b9a\u6b27\u6d32\u4e13\u5229\u4ee5\u53ca\u6b27\u6d32\u4e13\u5229\u7684\u5fb7\u56fd\u90e8\u5206\u81ea\u5176\u6388\u6743\u516c\u5e03\u4e4b\u65e5\u8d77\u6709\u6548<br \/>\n\u675c\u585e\u5c14\u591a\u592b\u5730\u65b9\u6cd5\u9662\uff1a<br \/>\n2022 \u5e74 9 \u6708 22 \u65e5\u5224\u51b3\uff0cAz. 4 b O 54\/22\uff1a<br \/>\n\u6b27\u6d32\u4e13\u5229\u53ca\u5176\u5fb7\u56fd\u90e8\u5206\u7684\u6709\u6548\u6027\u63a8\u5b9a\u95ee\u9898<\/p>\n<p>[2] \u5fb7\u56fd\u6700\u9ad8\u6cd5\u9662, BGH \u2013 Fulvestrant (X ZR 59\/17; \u6807\u9898\u6ce8\u91ca)<\/p>\n            <\/div>\n                            <div class=\"col-lg-10 text-start\">\n                <div class=\"autorbox row\">\n                \n                <div class=\"col-4 col-lg-2\">\n                <a href=\"https:\/\/pruefer.eu\/team\/dr-susanne-sonnenhauser\/\">\n                    <img decoding=\"async\" src=\"https:\/\/pruefer.eu\/wp-content\/uploads\/2022\/08\/Unbenannt-1_0000s_0000_IMG_0403-S.-Sonnenhauser.jpg\" \/>\n                <\/a>\n                    <\/div>\n                    <div class=\"col-8\">\n                    <a href=\"https:\/\/pruefer.eu\/team\/dr-susanne-sonnenhauser\/\">\n                    \u4f5c\u8005              \n                \n                   <div class=\"name\"> Dr. Susanne Sonnenhauser<\/div>\n                  \n                   Dr. Susanne Sonnenhauser (\u82cf\u73ca\u5a1c \u677e\u6069\u8c6a\u6cfd\u5c14\u535a\u58eb)\u81ea 2005 \u5e74\u4ee5\u6765\u4e00\u76f4\u4ece\u4e8b\u77e5\u8bc6\u4ea7\u6743\u9886\u57df\u7684\u5de5\u4f5c\uff0c\u62e5\u6709\u5fb7\u56fd\u4e13\u5229\u5f8b\u5e08\u548c\u6b27\u6d32\u4e13\u5229\u5f8b\u5e08\u8d44\u683c\u3002\u5e76\u4e8e 2008 \u5e74\u52a0\u5165 Pr\u00fcfer &amp; Partner\u666e\u5f8b\u4e30\u77e5\u8bc6\u4ea7\u6743\u5f8b\u5e08\u4e8b\u52a1\u6240\u3002\u5979\u7684\u4e3b\u8981\u6267\u4e1a\u9886\u57df\u662f\u4e13\u5229\u548c\u5546\u6807\u6cd5\uff0c\u5185\u5bb9\u6d89\u53ca\u5236\u836f\u548c\u751f\u547d\u79d1\u5b66\u9886\u57df\uff0c \u4e14\u5728\u4e13\u5229\u6388\u6743\u548c\u5f02\u8bae\u7a0b\u5e8f\u4e2d\u4ee3\u8868\u5979\u7684\u5ba2\u6237\u3002\u6b64\u5916\uff0c\u5979\u8fd8\u5728\u77e5\u8bc6\u4ea7\u6743\u7684\u6709\u6548\u6027\u548c\u4fb5\u6743\u95ee\u9898\u65b9\u9762\u63d0\u4f9b\u4e13\u5bb6\u54a8\u8be2\u3002\r\n                <\/a>\n                    <\/div>\n                    \n                    <div class=\"col-lg-2 cat\">\n                 \u53d1\u5e03\u65e5\u671f<div class=\"medium\">19. 3 \u6708 2024<\/div>                 \u5206\u7c7b<div class=\"medium\">UPC-Updates<\/div>                    <\/div>\n                <\/div>\n            <\/div>\n            \n            <div class=\"col-12 text-center mt-5\">\n            <p><a class=\"btn btn-primary text-white\" href=\"\/news\">\u5230\u65b0\u95fb\u9875\u9762<\/a><\/p>\n            <\/div>\n        <\/div>   \n    <\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>UPC \u7684\u9996\u6279\u88c1\u51b3\u5df2\u7ecf\u4e0b\u8fbe\uff0c\u4e86\u89e3 UPC \u5728\u5e7f\u6cdb\u8ba8\u8bba\u7684\u6743\u5229\u8981\u6c42\u89e3\u91ca\u3001\u4e8b\u5b9e\u9648\u8ff0\u548c\u4e3e\u8bc1\u8d23\u4efb\u4ee5\u53ca\u521b\u9020\u6027\u8003\u8651\u7b49\u95ee\u9898\u4e0a\u7684\u7acb\u573a\u5c06\u662f\u4ee4\u4eba\u5174\u594b\u7684\u3002<\/p>\n","protected":false},"author":12,"featured_media":13175,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[178],"tags":[],"class_list":["post-13284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-upc-updates-zh-hans"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u4ece UPC \u7684\u89d2\u5ea6\u6765\u770b\u6743\u5229\u8981\u6c42\u7684\u89e3\u91ca\u3001\u9648\u8ff0\u8d23\u4efb\u548c\u4e8b\u5b9e\u8bc1\u660e - UPC_CoA_335\/2023 - Pr\u00fcfer &amp; 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